Definition of "high-risk" []

• Of, relating to, or characterized by risk: a high-risk business. (adjective)
• Being particularly subject to potential danger or hazard: a high-risk surgical procedure. (adjective)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

• "Breast cancer patients that are classified as high-risk have been shown to still reap the benefits of Herceptin as long as four years after they have stopped using this treatment."
• "In the low-risk group, only 7 percent had aggressive cancer, compared with 40 percent of the men classified as high-risk, they found."
• "Garrido was rightly classified as a high-risk offender after he served his federal prison sentence, but the federal probation office "failed to supervise him accordingly," Ware wrote after reviewing the report: Home visits were rare and his probation officer never talked with neighbors or local law enforcement."