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Definition of "microhomology" []

  • The presence of the same short sequence of bases in different genes (noun)

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Use "microhomology" in a sentence
  • "Several studies have predicted that some CNV and nonrecurring copy number changes (CNC) in cancer cell lines, which are induced by aphidicolin or occur in some cases of Duchenne muscular dystrophy, Smith-Magenis syndrome, and Pelizaeus-Merzbacher disease, originate from nonhomologous end joining, fork stalling and template switching, or microhomology/microsatellite-induced replication mechanisms"
  • "(A) Infection-induced host DNA (green) double strand-break (DSB) and integration of kDNA minicircle sequence (blue) mediated by microhomology end-joining."
  • "The occurrence of minicircles linked to LINE sequences via AC-rich microhomology-mediated recombination may augment endogenous levels of recombination, thus explaining the active generation of mosaic sequences and minicircle hitchhiking along with their associated retroposon, as seen in germ-line cells of Chagas patients and their progeny."
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