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Definition of "lyase" [lyase]

  • Any of a group of enzymes that catalyze the formation of double bonds by removing chemical groups from a substrate without hydrolysis or catalyze the addition of chemical groups to double bonds. (noun)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

Use "lyase" in a sentence
  • "Garcinia Cambogia: is a natural form of Hydroxcitric acid (HCA) which can inhibit an enzyme in cells, citrate lyase, which is needed for the conversion of carbohydrates into fat."
  • "HCA has been thought to suppress enzymatic activity of citrate lyase which is responsible for lipogenesis and fatty acid biosynthesis."
  • "Previously reported Phase 2a results of LX2931, an inhibitor of sphingosine-1-phosphate lyase, demonstrated a favorable safety profile at all doses tested and suggested that rheumatoid arthritis patients treated with 150 mg of LX2931 once daily showed improvement in the primary efficacy endpoint of the study, the percentage of patients achieving an American College of Rheumatology 20 ACR20 response at week 12."