Definition of "aldose" [aldose]

• Any of a class of monosaccharide sugars containing an aldehyde group. (noun)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

• "It has been proposed that the open chain aldose while on the enzyme undergoes torsional inversion at the C2-C3 bond before ring closing."
• "They also reported that activity of the enzyme, known as aldose reductase, can be significantly reduced by compounds that have already undergone clinical trials as treatments for complications of diabetes."
• "NFAT5 regulates the adaptation of mammalian cells to hypertonic stress by inducing the expression of osmoprotective gene products that include chaperones and a number of enzymes and transporters, such as aldose reductase (AR), whose collective function is to increase the intracellular concentration of compatible organic osmolytes that allow cells to adapt and survive in a hypertonic environment"