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Definition of "calmodulin" [calmodulin]

  • A calcium-binding protein found in all nucleated cells that affects the activity of many calcium-sensitive enzymes, including those involved in muscular contraction. (noun)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

Use "calmodulin" in a sentence
  • "The team, which included researchers from Vanderbilt University, showed in theory that it might be possible to use drugs that maintain the positive effects on heart function of a known enzyme called calmodulin kinase II (CaM kinase) while reducing its negative effects."
  • "Researchers knew that an enzyme called calmodulin kinase II is overactive in several heart diseases and believed it played a role in the leaky channels - a tiny pore that controls release of calciu through the cell's membrane."
  • "While a molecule known as calmodulin is known to provide feedback control for calcium ion channels, the specific mechanism by which it down-regulates an ion channel is not clear."