Definition of "angioedema" []

• Swelling of the lower layers of the skin, often around the mouth, or of the mucosa or submucosa of the mouth or throat which can appear quickly in response to an allergen or due to other conditions (noun)

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• "While hives develop on the skin's surface, angioedema is a swelling of the deeper layers of the skin."
• "Yes, certainly, perhaps in brief because I think the science here has a number of complexities, but suffice to say the contact inhibition pathway and the centrality of kallikrein driving both bradykinen mechanisms primary which result in the edema and vascular shift so that where you have the surgical indications, but the role of the kallikrein bradykinen pathway has been very well established no just in HAE but also in other conditions such as acquired angioedema, which is due to the acquired as opposed to inherited deficiency of C1 inhibitor and so that is a very natural place to go."
• "We started IVs and gave him all the standard "angioedema" medications."