To cause damage, disruption, or destruction.(verb)
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Use "wreak havoc" in a sentence
"They do know, however, that when regulatory T cells lack a proper education, or when regulatory T cells are not formed in sufficient quantity in the thymus, antigen-seeking T cells can be suddenly freed to wreak havoc in the body, turning on both foreign antigens and body tissue at will, with nothing to tell them to stop."
"High-glycemic-index foods will cause you to have higher peaks in blood sugar and can wreak havoc on your insulin regulation."
"Erupting inflation and drastic devaluations can wreak havoc on business plans and operations."