Definition of "vigabatrin" []

• An anticonvulsant that inhibits the catabolism of GABA by irreversibly inhibiting GABA transaminase. (noun)

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• "Catalyst is also developing CPP-115, another GABA aminotransferase inhibitor that is more potent than vigabatrin and has reduced side effects e.g., visual field defects, or VFDs from those associated with vigabatrin."
• "The presentation discussed the medical relevance of GABA aminotransferase inactivators in the treatment of epilepsy and drug addiction, the history of the discovery of CPP-115, a detailed mechanistic analysis of GABA-AT inactivators, and a summary of CPP-115's pharmacological properties, including its superior visual safety profile and potency compared to vigabatrin."
• "Catalyst has two products in development, and is currently evaluating its lead product and first-in-class GABA aminotransferase inhibitor candidate, CPP-109 vigabatrin, for the treatment of cocaine addiction."