Definition of "vasoconstrictive" [vasoconstrictive]

• That causes vasoconstriction (adjective)

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• "Your article failed to mention that GSK's concern related to an unsubstantiated theory being advanced by Dr. Mary Money that these adverse events were due to a direct vasoconstrictive effect on the pulmonary circulation, which could lead to a condition known as primary pulmonary hypertension."
• "Due to concerns about potential adverse vasoconstrictive effects on regional vascular beds, such as the liver and the kidney, norepinephrine traditionally had either not been used or had been reserved as a last resort in a moribund patient, with predictably poor results."
• "Thus, large doses of the drug may be required in some patients with septic shock, possibly due to α-receptor down-regulation in sepsis. 111 Cardiovascular Effects Norepinephrine therapy usually causes a clinically significant increase in MAP attributable to its vasoconstrictive effects, with little change in HR or cardiac output, leading to increased systemic vascular resistance."