Definition of "up-regulation" []

• Alternative spelling of upregulation. (noun)

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• "In short, the authors found that the fat tissue from the obese co-twins showed a significant up-regulation of inflammatory pathways, significantly reduced mitochondrial DNA copy number, and disturbed mitochondrial energy metabolism — statistically most significantly, the decreased catabolism of branched-chain amino acids (BCAA)."
• "Kavlock says the screens test for a range of end points, such as interactions with nuclear receptors, up-regulation of the p53 tumor suppressor gene, and effects on DNA repair mechanisms."
• "Sex-dependent up-regulation of two splicing factors, Psf and Srp20, during hippocampal memory formation."