Definition of "troglitazone" []

• An oral antidiabetic agent that lowers blood glucose by improving the response of target cells to insulin without increasing insulin secretion. (noun)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

• "Medications such as troglitazone are used now to treat inflammatory diseases in adults, and we have demonstrated that these drugs have the ability to reverse the inflammatory effects of phthalates in white blood cells, "Weinberger said."
• "Liver toxicity is a common problem of approved drugs that has led to recalls of high profile drugs such as troglitazone (Rezulin"
• "Other drugs approved by the FDA and later found to cause harm include dexfenfluramine, a diet drug whose post-marketing data indicated an increased risk of pulmonary hypertension, and troglitazone, a diabetes drug that carried with it the risk of liver failure and was later pulled from the market."