A proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis)(noun)
WordNet. Princeton University. 2010.
Use "tnf" in a sentence
"Mississippi Half-Step Uptown Toodleloo permalink #2 of 64: from BILL M. (tnf)"
"Sekiguchi N, Kawauchi S, Furuya T, Inaba N, Matsuda K, et al. (2008) Messenger ribonucleic acid expression profile in peripheral blood cells from ra patients following treatment with an anti-tnf-alpha monoclonal antibody, infliximab."
"A, Sylvester J, Li WQ, Huang W, Dehnade F, et al. (2003) Induction of matrix metalloproteinase-13 gene expression by tnf-alpha is mediated by map kinases, ap-1, and nf-kappab transcription factors in articular chondrocytes."