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Definition of "thioguanine" []

  • A derivative of guanine obtained by replacing the carbonyl group with a thiol; it is an antineoplastic agent (noun)

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Use "thioguanine" in a sentence
  • "Our research was untargeted, and the line of inquiry we had begun in the 1940s yielded new drug therapies for malaria (pyrimethamine), leukemia (6-mercaptopurine and thioguanine), gout (allopurinol), organ transplantation"
  • "Stimulated by this finding Elion and Hitchings continued their research which soon resulted in two new chemotherapeutic drugs, thioguanine (1950) and"
  • "Meanwhile, the pursuit of 6-MP, thioguanine, azathioprine and allopurinol had occupied 20 years."