Advertisement - Continue reading below

Definition of "sickle" [sic•kle]

  • An implement having a semicircular blade attached to a short handle, used for cutting grain or tall grass. (noun)
  • The cutting mechanism of a reaper or mower. (noun)
  • To cut with a sickle. (verb-transitive)
  • To deform (a red blood cell) into an abnormal crescent shape. (verb-transitive)
  • To assume an abnormal crescent shape. Used of red blood cells. (verb-intransitive)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

Use "sickle" in a sentence
  • "Nutrition supplementation studies in sickle cell disease"
  • "A randomized, multicenter, phase II study to evaluate the safety and efficacy of oral ICL670 (deferasirox) 20 mg/kg/day relative to subcutaneous deferoxamine in sickle cell disease patients with iron overload from repeated blood transfusions"
  • "Commemorating a key event in sickle cell disease history"