Definition of "saquinavir" []

• A protease-inhibiting drug usually used in combination with other drugs to suppress the replication of HIV. (noun)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

• "The new era in treatment started last December, when Hoffman-La Roche introduced saquinavir (brand name Invirase), and it took off in March with the arrival of Merck's indinavir (Crixivan) and Abbott Laboratories 'ritonavir (Norvir)."
• "In September 1995, Howley started on a new combination of drugs, including two that had just been rushed onto the market, Norvir and saquinavir."
• "They found that serum taken from people who were taking antiretroviral therapy - which included ritonavir-boosted saquinavir (Invirase) or lopinavir (Kaletra) - showed significant antimalarial activity."