Definition of "proteostasis" []

• Eukaryotic protein homeostasis (noun)

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• "This biological machinery controlling the folding and function environment of the cell is referred to as the proteostasis network and is central for life."
• "Based on earlier studies of the folding environment required for CFTR function published in the journal Cell, the scientists reasoned that altering HDAC function might also rebalance proteostasis networks in the cell to favor functional restoration."
• ""By rebalancing the proteostasis program to provide a more supportive cellular environment," said Balch, "the cells appear to treat the mutation more like a polymorphism [genetic differences that are responsible for individual diversity] rather than something dangerous needing to be completely eliminated.""