Definition of "procarbazine" []

• A potent antineoplastic drug, C12H19N3O, used primarily to treat advanced Hodgkin's disease. (noun)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

• "For the past decade, a modified chemotherapy regimen consisting of cyclophosphamide, vincristine, procarbazine and prednisone (COPP), together with adriamycin, bleomycin and vinblastine (ABV) has been used to treat patients with HD."
• "This modified regimen contained less cyclophosphamide and procarbazine, agents known to impair fertility."
• "Methotrexate was substituted with a more powerful agent, procarbazine, and the duration of treatment was lengthened from two and a half months to six months."