The more or less ornamental border put around a picture to protect it and to isolate it, by separating it from other pictures, the decoration of the wall, etc.(noun)
The Century Dictionary (Public Domain)
Use "picture-frame" in a sentence
"On Dec. 6, 1996, Illingworth, a mild-mannered, former picture-frame manufacturer, visited Allen's office near John Wayne"
"Now, we've brought it into the digital picture-frame lab and compared it to several frames, including our top-rated model, the Digital Spectrum Memory Frame MF-801, $70."
"Any change, even a picture-frame nail in the wall, would set off the alarm."