Definition of "paracrine" [paracrine]

• Describing a hormone or other secretion released from endocrine cells into the surrounding tissue rather than into the bloodstream (adjective)

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• "But it has not been possible to detect chemical messages that travel between cells that are nearby but not in contact - called paracrine signals - because they are highly localized and they are produced in concentrations that have been below detection levels."
• "As such, these cells have the potential to move the regenerative medical field beyond the classic paracrine mechanisms neoangiogenesis and down-regulation of inflammation toward tissue and bone repair and regeneration."
• "They also noted that adipose tissue itself is a source for a number of paracrine factors that might affect retinal ganglion cells."