Definition of "osteocalcin" [osteocalcin]

• A protein found in bone and dentin, manufactured by osteoblasts. It plays a role in mineralization and calcium ion homeostasis. (noun)

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• "Early this year, Dr. Karsenty's team published a study demonstrating that in mice a protein called osteocalcin, which is produced by bone-forming cells called osteoblasts, binds to a specific receptor on cells of the testes."
• "The first clue that the skeleton may have an important role in regulating blood glucose came in 2007 when Dr. Karsenty discovered that a hormone released by bone - known as osteocalcin - can regulate glucose levels."
• "For our bones to be optimally healthy, one of the proteins found in bone-a protein called osteocalcin-needs to be chemically altered through the process of carboxylation."