Definition of "noncovalent" [noncovalent]

• Describing a form of bonding between large molecules that does not involve discrete bonds betwen pairs of atoms (adjective)

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• "The issue is the reappearance of a very stable, noncovalent protein-protein coupling."
• "One such possibility is that the initial version did not involve a covalent linkage to an amino acid, but merely noncovalent binding, producing a modest acceleration of peptide bond formation by virtue of positioning the reactants and reducing the entropic barrier to reaction."
• "For example, the strength of the electric charge allows both the strong (covalent) and the weak (noncovalent) chemical bonds necessary for proteins to work."