Definition of "mesocortical" [mesocortical]

• Of or pertaining to the mesocortex. (adjective)

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• "ITI-007 also exhibits mesocortical and mesolimbic selectivity as evidenced by regionally selective increases in dopamine release and phosphorylation of glutamatergic NMDA NR2B receptors in response to dopamine D1 receptor activation."
• "Given the unique pharmacological profile of ITI-007 that includes potent 5-HT2A receptor antagonism, pre-synaptic partial agonism and post-synaptic antagonism of D2 receptors, and functional mesolimbic/mesocortical selectivity of dopaminergic and glutamatergic interactions,"