Definition of "lose it" [lose it]

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Use "lose it" in a sentence

"Damn it to hell— He let loose with a string of curses as he thrust his gun into his holster and wrapped his arms around her before she could totally lose it and slide bonelessly to the floor."
"Ally Pete-Robbins will lose it if she sees a scratch."
"In Chapter 4, we will talk about how caloric restriction works, how much weight you are going to lose, and how fast you are going to lose it with the Fiber35 Diet."

Words like "lose it"

act behave blow one's top die

dissolve do fall apart freak out

go ape go apeshit go snake go to pieces

hit the ceiling hit the roof lose one's rag lose one's temper