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To be unsuccessful in retaining possession of; mislay: He's always losing his car keys.
(verb-transitive)
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To be deprived of (something one has had): lost her art collection in the fire; lost her job.
(verb-transitive)
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To be left alone or desolate because of the death of: lost his wife.
(verb-transitive)
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To be unable to keep alive: a doctor who has lost very few patients.
(verb-transitive)
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To be unable to keep control or allegiance of: lost his temper at the meeting; is losing supporters by changing his mind.
(verb-transitive)
American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.