Definition of "leupeptin" [leupeptin]

• A protease inhibitor that also inhibits calpain (noun)

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• "Tissues were homogenized in a lysis buffer consisting of 10 mM Hepes, 1% Triton X-100, and protease inhibitor cocktail, including aprotinin, leupeptin, pepstatin A, Bestatin, E-64,"
• "DTT, phosphatase inhibitors (0.1 µM okadaic acid and 1 mM sodium orthovanadate) and protease inhibitors (1 mM PMSF and 10 µg/ml leupeptin) using a motorized teflon-glass homogenizer."
• "Cell extracts were obtained with RIPA buffer in the presence of protease inhibitors (sodium pyrophosphate, sodium fluoride, phenylmethanesulfonyl fluoride, pepstatin A, aprotinin, leupeptin, antipain, benzamidine - all from Sigma)."