Definition of "leukoencephalopathy" [leukoencephalopathy]

• Any disease that effects the white matter of the brain (noun)

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• "A Biogen spokeswoman said the company worked with the Food and Drug Administration on the change, which includes a table that details the incidence of progressive multifocal leukoencephalopathy, or PML."
• "Its joint venture partner on Tysabri, U. S.-based Biogen Idec, suspended Tysabri in the U.S. in 2005 after two patients using combination therapy contracted a rare brain infection, progressive multifocal leukoencephalopathy or PML."
• "Some patients taking the drug developed a rare infection—progressive multifocal leukoencephalopathy, or PML—and two patients died."