Definition of "leflunomide" [leflunomide]

• An inhibitor of pyrimidine synthesis, used to treat some forms of arthritis. (noun)

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• "Tests showed that the drug, leflunomide, significantly reduced tumour growth in mice with human-like melanoma."
• "The effect was even more powerful when leflunomide was combined with an experimental melanoma drug called PLX4720."
• "The stage is now set for clinical trials to investigate the effect of leflunomide on melanoma patients."