Definition of "irinotecan" [irinotecan]

• A particular drug used in chemotherapy. (noun)

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• "In mid-May 2011, Enzon announced plans to halt the development of PEG-SN38 (EZN-2208), a PEGylated version of the active metabolite of the cancer drug, irinotecan, for the treatment of metastatic colorectal cancer (mCRC)."
• "PEG-SN38 or EZN-2208 is Enzon's PEGylated form of SN38, the active metabolite of the cancer drug Camptosar® (irinotecan HCl injection)."
• "-- July 2008 (Japan): for use in combination with irinotecan in patients with EGFR-expressing mCRC who have failed prior irinotecan therapy"