Definition of "integrin" [integrin]

• Any of many heterodimeric transmembrane proteins that function as receptors in communication between cells. (noun)

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• "In addition, Merck is developing cilengitide, which is the first in a new class of investigational anti-cancer therapies called integrin inhibitors to reach Phase III of development; it is currently being investigated for the treatment of glioblastoma, SCCHN and NSCLC."
• "In addition, Merck is developing cilengitide, which is the first in a new class of investigational anti-cancer therapies called integrin inhibitors to reach Phase III of development; it is currently being investigated for the treatment of glioblastoma,"
• "Through their study, they identified a molecule - called LXY1 - that binds with high specificity to a particular cell-surface protein called alpha-3 integrin, which is overexpressed on cancer cells."