Any data processing system, either manual or computerized(noun)
Any telecommunications system whose primary function is to transmit and/or display data(noun)
Wiktionary.org : Text is available under the Creative Commons Attribution-ShareAlike License
Use "information system" in a sentence
"Nonetheless, Johnson and Rostow maintained the three core elements of the Kennedy-Bundy innovations: the adviser handling the presidents day-to-day foreign affairs business; the staff recruited to serve the current administration; and the communications and information system centered in the Situation Room."
"The final case describes how the “Thai Farmers Bank” makes a majorinvestment in a computerized information system to overcome the competitive disadvantage caused by a rival’s institution of an automatic teller system."