That cannot permeate through a specified semipermeable membrane(adjective)
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Use "impermeant" in a sentence
"Some molecules move freely across the membrane, some are impermeant or very slowly permeant, and some move across the membrane depending upon pH."
"Organelles are bounded by impermeant, lipid-rich membranes that ensure the physical and functional separation of vital biochemical processes."
"When the researchers introduced its associated membrane-impermeant fluorogen, it bound to the FAP-tagged GPCR on the cell surface, emitting a bright fluorescent glow."