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Use "handicaps" in a sentence
"A smart and intelligent lawyer who, in spite of her gender and racial handicaps, is actually more than one dimensional and doesn't fit into the cultural stereotypes he's come to rely on ever since he saw West Side Story."
"Mr. Dodd was hired by the studios, in part, because of the potential long-term benefits of his Washington connections and clout, despite the obvious short-term handicaps."
"People such as scientist Stephen Hawking wouldn't have a chance in the U.K., where the National Health Service would say the life of this brilliant man, because of his physical handicaps, is essentially worthless."