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Deep mental anguish, as that arising from bereavement. See Synonyms at regret.
(noun)
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A source of deep mental anguish.
(noun)
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Annoyance or frustration: Trying to follow their directions was nothing but grief.
(noun)
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Trouble or difficulty: the griefs of trying to meet a deadline.
(noun)
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Archaic A grievance.
(noun)
American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.