Definition of "glucocerebrosidase" [glucocerebrosidase]

• An enzyme that is needed to cleave, by hydrolysis, the beta-glucosidic linkage of glucocerebroside, an intermediate in glycolipid metabolism, and mutations in which cause Gaucher's disease. (noun)

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• "For example, people with Gaucher disease are deficient in the enzyme glucocerebrosidase, which is responsible for breaking down a certain fat molecule called glucocerebroside."
• "Currently, several biotechnology companies have used plant biotechnology to produce protein pharmaceuticals, such as glucocerebrosidase to treat Gaucher disease in our case, lipase to treat cystic fibrosis, alpha-interferon, lactoferrin, and others, which are under evaluation in human studies"
• "Taliglucerase alfa, the Company's proprietary plant-cell expressed form of glucocerebrosidase GCD, is in development for the treatment of Gaucher disease."