(genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism(noun)
WordNet. Princeton University. 2010.
Use "genetic mutation" in a sentence
"Breeds of dog with very short legs, like basset hounds and dachshunds, acquired them in a single step with the genetic mutation called achondroplasia, a classic example of a large mutation that would be unlikely to survive in nature."
"Roche's vemurafenib works in a very different way, by blocking a genetic mutation known as BRAF, which may help the disease grow."