Definition of "gefitinib" [gefitinib]

• A drug, used in the treatment of certain types of cancer, that acts in a similar way to erlotinib by selectively targeting the mutant proteins in malignant cells. (noun)

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• "Giving women with early breast cancer a drug called gefitinib (Iressa) before surgery could reduce t ..."
• "Specifically, we show that responsiveness to alternative HER-targeted inhibitors, such as gefitinib and cetuximab, is dramatically potentiated by long-term trastuzumab treatment of ovarian cancer cells."
• "Emerging evidence indicates that cMET inhibition may be useful in the treatment of certain cancers, including gastric and kidney cancer [2], and may help to overcome resistance to some targeted therapies, such as gefitinib in non-small cell lung cancer [3]."