Definition of "farnesyltransferase" []

• One of the three enzymes in the prenyltransferase group, believed to play an important role in development of progeria and various cancers. (noun)

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• "Tipifarnib is classified under drugs known as farnesyltransferase inhibitors (FTIs), which are being tested in people with myeloid leukemia, neurofibromatosis and other conditions."
• "Tipifarnib belongs to a class of drugs known as farnesyltransferase inhibitors (FTIs), which are being tested in people with myeloid leukemia, neurofibromatosis and other conditions."
• "In our experiments, inhibition of c-Ras by farnesyltransferase inhibitors and a dominant negative form of H-Ras (Ras S17N) suppressed muscle differentiation."