Definition of "depolarization" [de•po•lar•i•za•tion]

• The act of depriving of polarity, or the result of such action; reduction to an unpolarized condition. (noun)

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• "This is the effect to which the term 'depolarization' has been applied; the experiment really proving that with both light and heat we have the same resolution by the plate of mica, and recompounding by the analyzer, of the ethereal vibrations."
• "The doubts thus thrown upon the question were removed by the experiments of Forbes, who first established the polarization and 'depolarization' of heat."
• "Locally it blocks the initiation and propagation of nerve impulses along an axon by interference with sodium permeability during depolarization. 3,11 Centrally it blocks the presynaptic reuptake of norepinephrine and dopamine."