Used up, expended; of which nothing is left.(adjective)
Simple past tense and past participle of deplete.(verb)
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Use "depleted" in a sentence
"But balancing that is the fact that as our farming has intensified, nutrients have been depleted from the soil, so that a zucchini today has fewer nutrients that a zucchini bought 100 years ago."
"The rapid rate at which our forests are being depleted is causing the high cost of lumber today, and it may be of interest to many to know that the average increase of one acre of mixed timber trees is 14 ft. of sawed lumber per year."
"In the West, keeping them green is draining what little water is left in depleted water-tables."