Simple past tense and past participle of depeople.(verb)
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Use "depeopled" in a sentence
"More haunting images of ruins, depeopled cities, and Gothic landscapes come from this gallery of abandoned places."
"Every man has within him only one life and one nature to give to the service of God, and if there was but one way of doing that, celibate within the cloister, procreation and birth would cease, the world would be depeopled, and neither within nor without the Church would God receive worship."
"The house was emptier than ever, half-depeopled by death and guilt, and the burden that fell back upon Judith's shoulders was the heavier by two childless widows for whom she must make provision."