Definition of "cyclooxygenase" [cyclooxygenase]

• Any of several enzymes that catalyze the conversion of arachidonic acid into prostaglandins; their inhibition is the mode of action of aspirin and ibuprofen. (noun)

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• "The researchers focused on an enzyme known as cyclooxygenase-2 (COX-2), which is involved in a variety of physiologic functions, from regulating blood pressure to controlling inflammation and contracting muscles."
• "The researchers focused on an enzyme known as cyclooxygenase-2 COX-2, which is involved in a variety of physiologic functions, from regulating blood pressure to controlling inflammation and contracting muscles."
• "Bowel cancer is the number two and number three killer in the US and the UK respectively. liquorice may be related to another enzyme, called cyclooxygenase 2 (COX-2), which is reported to promote colorectal cancer progression"