Definitions, Translations, and Word of the Day
Definition of "castrate" [cas•trate]
- To remove the testicles of (a male); geld or emasculate. (verb-transitive)
- To remove the ovaries of (a female); spay. (verb-transitive)
- To deprive of virility or spirit; emasculate. (verb-transitive)
- An individual who is incapable of reproduction as a result of removal, destruction, or inactivation of the gonads. (noun)
American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Use "castrate" in a sentence
- "Preliminary results of the company's ongoing Phase I/IIa clinical trial with Apoptone (HE3235) for hormone-resistant prostate cancer (also called castrate-resistant prostate cancer or CRPC) were presented on November 16, 2009 at the Molecular Targets and Cancer Therapeutics Conference."
- "The trial involved 1,432 men with so-called castrate-resistant prostate cancer who were randomly assigned to receive injections every four weeks of denosumab or a placebo."
- "Ellen lay out for me every way that she had seen me "castrate" men, or knew that I had by the result."
Words like "castrate"