Definition of "carboxylase" []

• An enzyme that catalyzes a carboxylation or decarboxylation reaction. (noun)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

• "Deficiencies of pyruvate dehydrogenase (PDH) and pyruvate carboxylase (PDH and PC); Leigh syndrome"
• "In the initial step of the Calvin Cycle, carbon dioxide (from the atmosphere) reacts with a five-carbon compound, ribulose bisphosphate (RuBP), in a reaction that is catalyzed by the enzyme RuBP carboxylase/oxygenase ( "RuBisco")."
• "The physical separation of H - from D-labeled molecules made possible by their different rates of reaction was used to establish that the transfer of hydrogen in G6P isomerase was intramolecular9 and that the site of attachment of CO2 to ribulose-1, 5-P2 to produce two molecules of phosphoglyceric acid had to be to C-2 rather than C-4 in the RUDP carboxylase reaction47."