Definition of "calcineurin" [calcineurin]

• A protein phosphatase that stimulates the growth and differentiation of T cells (noun)

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• "Elidel belongs to a class of drugs known as calcineurin inhibitors, so called because they reduce immune activity by inhibiting the activity of the enzyme calcineurin."
• "AKAP5 protein domains that interact with other signaling molecules, such as calcineurin, have been mapped to regions still present in the D36 protein"
• "This is of clinical relevance because cyclosporine A is a known inhibitor of calcineurin."