Definition of "antithrombin" [antithrombin]

• A small molecule that inactivates several enzymes of the coagulation system. (noun)

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• "A recently published study used thrombelastometry, plasmatic coagulation parameters and platelet count to assess the coagulation system in septic patients before and during a short-term antithrombin therapy."
• "The European Medicines Evaluation Agency (EMEA) may decide early next year on approval of an anticoagulant protein, human antithrombin, that is produced in goat's milk to treat a hereditary disorder."
• "And certainly this choice of caprine platform has paid off enormously; GTC can now boast a historical milestone with the release of "ATryn®, our recombinant form of human antithrombin, the first transgenically produced protein to be approved anywhere in the world, having recently been approved by the European Commission for the prophylactic treatment of deep vein thrombosis in patients with hereditary antithrombin deficiencies that are undergoing surgical procedures," according to a company statement."