Definition of "antisense" []

• Of or relating to a nucleotide sequence that is complementary to a sequence of messenger RNA. When antisense DNA or RNA is added to a cell, it binds to a specific messenger RNA molecule and inactivates it. (adjective)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

• "The researchers also suppressed CPE-delta N in mice using an experimental approach called antisense and found tumors implanted into the animals did not spread."
• "Isis Pharmaceuticals, Inc. engages in the discovery and development of a new class of drugs called antisense drugs using antisense technology, a novel drug discovery platform to generate"
• "Working with a class of compounds known as antisense phosphorodiamidate morpholino oligomers, or PMOs, scientists conducted studies in which nine rhesus monkeys were challenged with lethal Ebola virus, reports"