Definition of "antimetabolite" []

• A substance that closely resembles an essential metabolite and therefore interferes with physiological reactions involving it. (noun)

American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

• "When this process is allowed to proceed normally it is also called “metobolizing,” somethotrexate is also called an “antimetabolite.”"
• "Methotrexate is currentlythe only antimetabolite approved by the FDA as a treatment for psoriasis."
• "They prevented rabbits from producing antibody against human serum albumin by treating them for two weeks with the antimetabolite, 6-Mercaptopurine."