Alternating periods of good and bad fortune or spirits.(noun-plural)
American Heritage(R) Dictionary of the English Language, Fifth Edition. Copyright (c) 2011 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Use "ups and downs" in a sentence
"And my husband, Zenji, who has always been there through the hellish ups and downs of my health challenges and by being there has made all the difference."
"For numerous examples of assemblers sharing ups and downs with suppliers, see Nishiguchi, “Strategic Dualism,” pp."
"The ups and downs of raising a bipolar child : a survival guide for parents / Judith Lederman, Candida Fink."