Definition of "upregulate" [upregulate]

• To increase the number of cell receptors by using upregulation. (verb)

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• ""upregulate," or churn out, genes that make molecules that signal the immune system to throttle back; and they can "downregulate," or reduce the production of, genes that make molecules that carry signals between immune cells."
• "When phytonutrients and other molecules that contain the Michael acceptor–like pharmacophore upregulate the transcription factor NRF2, more than a dozen protective anti-inflammatory proteins in the cell are activated."
• "Upon activation, these transcription factors translocate to the nucleus of the cell, where they attach to receptor sites on the genes and upregulate, or turn on, their expression."