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Definition of "scid" []

  • Severe combined immune deficiency; a serious condition in which babies are born with reduced numbers of T- and B-lymphocytes, which impairs their immune systems and makes them susceptible to severe infections and cancer

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Use "scid" in a sentence
  • "Kneteman NM, Weiner AJ, O'Connell J, Collett M, Gao T, et al. (2006) Anti-HCV therapies in chimeric scid-Alb/uPA mice parallel outcomes in human clinical application."
  • "Gell D, Fox M, Taccioli GE, Lehmann AR, et al. (1996) Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse."
  • "In fact, an earlier approach in which an Fc-IL-7 fusion protein was delivered via weekly injections led to increased T cell: B cell ratios in the spleens of humanized NOD-scid γc -/- mice"
  • "Similar engraftment has also been observed upon injecting CD34+ CB cells into NOD/scid γc -/- (NSG) recipient mice"
  • "Lyons BL, Burzenski LM, Gott B, Chen X, et al. (2005) Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells."
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